2OPH: Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor

PDB ID: 2OPHDownload
MMDB ID: 46440
PDB Deposition Date: 2007/1/29
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2OPH: dimeric; determined by author and by software (PISA)
Molecular Components in 2OPH
Label Count Molecule
Proteins (2 molecules)
2
Dipeptidyl Peptidase 4 Soluble Form
(Gene symbol: DPP4)
Molecule annotation
Chemicals and Non-standard biopolymers (27 molecules)
1
22
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-acetamido-2-deoxy-alpha-D-glucopyranose2-acetamido-2-deoxy-alpha-D-glucopyranose
3
1
SODIUM IONSODIUM ION
4
2
N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDEN-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303